Darkness and the dawn?

Antiprotozoals for human African trypanosomiasis: the heart of darkness at dawn

In December 2012 the WHO convened an expert meeting on elimination of human African trypanosomiasis (HAT; sleeping sickness). The participants concluded that the decision to eliminate the disease should be maintained with a goal of elimination as a public health problem by 2020 and absence of transmission resulting in zero cases reported in all discrete geographic areas of endemicity, or ‘foci’...

The Dawn of Galaxies ∗

The development of primordial inhomogeneities into the non-linear regime and the formation of the first astrophysical objects within dark matter halos mark the transition from a simple, neutral, cooling universe – described by just a few parameters – to a messy ionized one – the realm of radiative, hydrodynamic, and star formation processes. The recent measurement by the WMAP satellite of a lar...

The Dawn of Litholapaxy

papers appeared by Surgeon P. J. Freyer, giving his experience of his first twenty cases of litholapaxy. In March 1884 (l.M.G.) Dr. Freyer gives an account of 57 more litholapaxies. In this paper he endeavours to estimate the value of the operation of litholapaxy. Of the 57 cases only two were fatal, one from peritonitis and the other from pyaemia. Dr. Freyer points out the importance of removi...

Fighting through the darkness.

flexibility and self-direction but also its daunting stress levels, has been both a blessing and a burden in my battle with depression. Depression, in turn, has not made it any easier to meet the challenges of academic life. I am fortunate to work in a department and at an institution that see younger faculty members as individuals to be invested in and supported. But the cost of depression to ...

Melatonin―the Hormone of Darkness